| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Large ribosomal subunit protein mL62 (7-57 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MRPL58 |
| Gene ID: |
3396 |
| Uniprot ID: |
ICT1_HUMAN |
| Immunogen Region: |
7-57 aa |
| Specificity: |
This antibody detects endogenous levels of ICT1 at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human ICT1 at the amino acid range 7-57 |
| Post Translational Modifications | Methylation of glutamine in the GGQ triplet by HEMK1. |
| Function | Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. Involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes. |
| Protein Name | Large Ribosomal Subunit Protein Ml6239s Ribosomal Protein L58 - MitochondrialMrp-L58Digestion Substraction 1Ds-1Immature Colon Carcinoma Transcript 1 ProteinPeptidyl-Trna Hydrolase Ict1 - Mitochondrial |
| Database Links | Reactome: R-HSA-5368286Reactome: R-HSA-5389840Reactome: R-HSA-5419276 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Large Ribosomal Subunit Protein Ml62 antibodyAnti-39s Ribosomal Protein L58 - Mitochondrial antibodyAnti-Mrp-L58 antibodyAnti-Digestion Substraction 1 antibodyAnti-Ds-1 antibodyAnti-Immature Colon Carcinoma Transcript 1 Protein antibodyAnti-Peptidyl-Trna Hydrolase Ict1 - Mitochondrial antibodyAnti-MRPL58 antibodyAnti-DS1 antibodyAnti-ICT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
