| Tissue Specificity | Present in kidney, liver, thymus and testis, and at lower level in brain and spleen (at protein level). |
| Function | Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins. |
| Protein Name | Large Ribosomal Subunit Protein Ml4139s Ribosomal Protein L41 - MitochondrialL41mtMrp-L41Bcl-2-Interacting Mitochondrial Ribosomal Protein L41Cell Proliferation-Inducing Gene 3 ProteinMrp-L27 Homolog |
| Database Links | Reactome: R-HSA-5368286Reactome: R-HSA-5389840Reactome: R-HSA-5419276 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Large Ribosomal Subunit Protein Ml41 antibodyAnti-39s Ribosomal Protein L41 - Mitochondrial antibodyAnti-L41mt antibodyAnti-Mrp-L41 antibodyAnti-Bcl-2-Interacting Mitochondrial Ribosomal Protein L41 antibodyAnti-Cell Proliferation-Inducing Gene 3 Protein antibodyAnti-Mrp-L27 Homolog antibodyAnti-MRPL41 antibodyAnti-BMRP antibodyAnti-MRPL27 antibodyAnti-RPML27 antibodyAnti-PIG3 antibody |
Information sourced from Uniprot.org
