| Host: | Rabbit |
| Applications: | ELISA/WB |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-MRGX1 (280-330) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | FITC |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.52-0.67 µg/µl |
| Dilution Range: | WB: 1:500 DB: 1:10, 000 ELISA: 1:10, 000 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | Mrgprx1 |
| Gene ID: | 282547 |
| Uniprot ID: | MRGX1_RAT |
| Immunogen Region: | 280-330 |
| Immunogen: | Synthetic peptide taken within amino acid region 280-330 on rat MrgX1 protein. |
| Tissue Specificity | Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. Associated preferentially with IB4 class of small-diameter somatosensory afferents (also known as nociceptors). |
| Function | Orphan receptor activated by neuropeptides terminating in Arg-Phe or Arg-Phe-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. May regulate the function of nociceptive neurons by modulation of pain perception. |
| Protein Name | Mas-Related G-Protein Coupled Receptor Member X1 Sensory Neuron-Specific G-Protein Coupled Receptor 1 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mas-Related G-Protein Coupled Receptor Member X1 antibody Anti-Sensory Neuron-Specific G-Protein Coupled Receptor 1 antibody Anti-Mrgprx1 antibody Anti-Mrgc antibody Anti-Mrgprc antibody Anti-Mrgprc11 antibody Anti-Snsr antibody Anti-Snsr1 antibody |
Information sourced from Uniprot.org