Anti-MRC2 antibody (121-170 aa) (STJ92921)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human MRC2 at the amino acid range 121-170
General Information
| Short Description | Rabbit polyclonal anti-C-type mannose receptor 2 (121-170 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MRC2 |
| Gene ID | 9902 |
| Uniprot ID | MRC2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human MRC2 at the amino acid range 121-170 |
| Immunogen Region | 121-170 aa |
| Specificity | Endo180 Polyclonal Antibody detects endogenous levels of Endo180 protein. |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs). |
| Protein Name | C-Type Mannose Receptor 2C-Type Lectin Domain Family 13 Member EEndocytic Receptor 180Macrophage Mannose Receptor 2Urokinase-Type Plasminogen Activator Receptor-Associated ProteinUpar-Associated ProteinUrokinase Receptor-Associated ProteinCd Antigen Cd280 |
| Database Links | Reactome: R-HSA-1236978 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-C-Type Mannose Receptor 2 antibodyAnti-C-Type Lectin Domain Family 13 Member E antibodyAnti-Endocytic Receptor 180 antibodyAnti-Macrophage Mannose Receptor 2 antibodyAnti-Urokinase-Type Plasminogen Activator Receptor-Associated Protein antibodyAnti-Upar-Associated Protein antibodyAnti-Urokinase Receptor-Associated Protein antibodyAnti-Cd Antigen Cd280 antibodyAnti-MRC2 antibodyAnti-CLEC13E antibodyAnti-ENDO180 antibodyAnti-KIAA0709 antibodyAnti-UPARAP antibody |
Information sourced from Uniprot.org