• Western blot analysis of lysates from SH-SY5Y, 293 cells, (Green) primary antibody was diluted at 1:1000, 4°C over night, secondary antibody was diluted at 1:10000, 37°C 1hour. (Red) loading contrl antibody was diluted at 1:5000 as loading control, 4°C over night, secondary antibody was diluted at 1:10000, 37°C 1hour.
  • Western blot analysis of lysates from 293 cells, using MRC2 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunofluorescence analysis of HepG2 cells, using MRC2 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MRC2 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using Endo180 Polyclonal Antibody diluted at 1：1000

Anti-MRC2 antibody (121-170 aa) (STJ92921)

SKU:
STJ92921

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-C-type mannose receptor 2 (121-170 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MRC2
Gene ID: 9902
Uniprot ID: MRC2_HUMAN
Immunogen Region: 121-170 aa
Specificity: Endo180 Polyclonal Antibody detects endogenous levels of Endo180 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human MRC2 at the amino acid range 121-170
Post Translational Modifications N-glycosylated.
Function May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).
Protein Name C-Type Mannose Receptor 2
C-Type Lectin Domain Family 13 Member E
Endocytic Receptor 180
Macrophage Mannose Receptor 2
Urokinase-Type Plasminogen Activator Receptor-Associated Protein
Upar-Associated Protein
Urokinase Receptor-Associated Protein
Cd Antigen Cd280
Database Links Reactome: R-HSA-1236978
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-C-Type Mannose Receptor 2 antibody
Anti-C-Type Lectin Domain Family 13 Member E antibody
Anti-Endocytic Receptor 180 antibody
Anti-Macrophage Mannose Receptor 2 antibody
Anti-Urokinase-Type Plasminogen Activator Receptor-Associated Protein antibody
Anti-Upar-Associated Protein antibody
Anti-Urokinase Receptor-Associated Protein antibody
Anti-Cd Antigen Cd280 antibody
Anti-MRC2 antibody
Anti-CLEC13E antibody
Anti-ENDO180 antibody
Anti-KIAA0709 antibody
Anti-UPARAP antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance