• Western blot analysis of extracts of various cell lines, using Mannose Receptor/CD206 antibody (STJ111269) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
  • Western blot analysis of various lysates using Mannose Receptor/CD206 Rabbit polyclonal antibody (STJ111269) at 1:2000 dilution. Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25  Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection:ECL Basic Kit. Negative control (NC) : Jurkat. Exposuretime: 30s.
  • Western blot analysis of extracts of various cell lines, using Mannose Receptor/CD206 antibody (STJ111269) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Anti-MRC1 antibody (610-1456) (STJ111269)

SKU:
STJ111269

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-MRC1 (610-1456) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:100-1:500
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MRC1
Gene ID: 4360
Uniprot ID: MRC1_HUMAN
Immunogen Region: 610-1456
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 610-1456 of human Mannose Receptor/CD206 (NP_002429.1).
Immunogen Sequence: GLWDVLKCDEKAKFVCKHWA EGVTHPPKPTTTPEPKCPED WGASSRTSLCFKLYAKGKHE KKTWFESRDFCRALGGDLAS INNKEEQQTIWRLITASGSY HKLFWLGLTYGSPSEGFTWS DGSPVSYENWAYGEPNNYQN VEYCGELKGDPTMSWNDINC EHLNNWICQIQKGQTPKPEP TPAPQDNPPVTEDGWVIYKD YQYYFSKEKETMDNARAFCK RNFGDLVSIQSESEKKFLW
Function Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. (Microbial infection) Acts as phagocytic receptor for bacteria, fungi and other pathogens. (Microbial infection) Acts as a receptor for Dengue virus envelope protein E. (Microbial infection) Interacts with Hepatitis B virus envelope protein.
Protein Name Macrophage Mannose Receptor 1
Mmr
C-Type Lectin Domain Family 13 Member D
C-Type Lectin Domain Family 13 Member D-Like
Human Mannose Receptor
Hmr
Macrophage Mannose Receptor 1-Like Protein 1
Cd Antigen Cd206
Database Links Reactome: R-HSA-1236978
Reactome: R-HSA-9637628
Cellular Localisation Endosome Membrane
Single-Pass Type I Membrane Protein
Cell Membrane
Alternative Antibody Names Anti-Macrophage Mannose Receptor 1 antibody
Anti-Mmr antibody
Anti-C-Type Lectin Domain Family 13 Member D antibody
Anti-C-Type Lectin Domain Family 13 Member D-Like antibody
Anti-Human Mannose Receptor antibody
Anti-Hmr antibody
Anti-Macrophage Mannose Receptor 1-Like Protein 1 antibody
Anti-Cd Antigen Cd206 antibody
Anti-MRC1 antibody
Anti-CLEC13D antibody
Anti-CLEC13DL antibody
Anti-MRC1L1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance