| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Monoclonal |
| Clone ID: |
S8MR |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MRC1 |
| Gene ID: |
4360 |
| Uniprot ID: |
MRC1_HUMAN |
| Immunogen Region: |
1357-1456 |
| Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 1357-1456 of human Mannose Receptor/CD206 (P22897). |
| Immunogen Sequence: |
RPKIIDAKPTHELLTTKADT RKMDPSKPSSNVAGVVIIVI LLILTGAGLAAYFFYKKRRV HLPQEGAFENTLYFNSQSSP GTSDMKDLVGNIEQNEHSVI |
| Function | Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. (Microbial infection) Acts as a phagocytic receptor for bacteria, fungi and other pathogens. (Microbial infection) Acts as a receptor for Dengue virus envelope protein E. (Microbial infection) Interacts with Hepatitis B virus envelope protein. |
| Protein Name | Macrophage Mannose Receptor 1MmrC-Type Lectin Domain Family 13 Member DC-Type Lectin Domain Family 13 Member D-LikeHuman Mannose ReceptorHmrMacrophage Mannose Receptor 1-Like Protein 1Cd Antigen Cd206 |
| Database Links | Reactome: R-HSA-1236978Reactome: R-HSA-9637628 |
| Cellular Localisation | Endosome MembraneSingle-Pass Type I Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Macrophage Mannose Receptor 1 antibodyAnti-Mmr antibodyAnti-C-Type Lectin Domain Family 13 Member D antibodyAnti-C-Type Lectin Domain Family 13 Member D-Like antibodyAnti-Human Mannose Receptor antibodyAnti-Hmr antibodyAnti-Macrophage Mannose Receptor 1-Like Protein 1 antibodyAnti-Cd Antigen Cd206 antibodyAnti-MRC1 antibodyAnti-CLEC13D antibodyAnti-CLEC13DL antibodyAnti-MRC1L1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
