| Host: | Goat |
| Applications: | Pep-ELISA/IHC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-MOZ/KAT6A (Internal) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Preliminary experiments in lysates of cell line U937 gave no specific signal but low background (at antibody concentration up to 1µg/ml).IHC: Paraffin embedded Human Adrenal Gland |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | KAT6A |
| Gene ID: | 7994 |
| Uniprot ID: | KAT6A_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_006757.2 |
| Specificity: | Reported variants NP_001092882.1, NP_006757.2, NP_001092883.1 represent identical protein. |
| Immunogen Sequence: | EKIKDKEETELD |
| Function | Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2. Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML. |
| Protein Name | Histone Acetyltransferase Kat6aMoz - Ybf2/Sas3 - Sas2 And Tip60 Protein 3Myst-3Monocytic Leukemia Zinc Finger ProteinRunt-Related Transcription Factor-Binding Protein 2Zinc Finger Protein 220 |
| Database Links | Reactome: R-HSA-3214847Reactome: R-HSA-6804758 |
| Cellular Localisation | NucleusNucleolusNucleoplasmPml BodyRecruited Into Pml Body After Dna Damage |
| Alternative Antibody Names | Anti-Histone Acetyltransferase Kat6a antibodyAnti-Moz - Ybf2/Sas3 - Sas2 And Tip60 Protein 3 antibodyAnti-Myst-3 antibodyAnti-Monocytic Leukemia Zinc Finger Protein antibodyAnti-Runt-Related Transcription Factor-Binding Protein 2 antibodyAnti-Zinc Finger Protein 220 antibodyAnti-KAT6A antibodyAnti-MOZ antibodyAnti-MYST3 antibodyAnti-RUNXBP2 antibodyAnti-ZNF220 antibody |
Information sourced from Uniprot.org
