| Host: | Chicken |
| Applications: | ICC/IHC/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Chicken polyclonal anti-Motor Neuron and Pancreas Homeobox Protein 1 for use in ICC, IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgY |
| Formulation: | Phosphate-buffered (10 mM) isotonic (0.9%, w/v) saline (“PBS, pH 7.2) with sodium azide (0.02%, w/v) added as a preservative." |
| Purification: | Affinity-Purified IgY |
| Concentration: | 200 µg/mL |
| Dilution Range: | WB 1:200-1:1000ICC 1:50-1:200 |
| Storage Instruction: | Store at 4°C in the dark. Under these conditions, the antibodies should have a shelf life of at least twelve months, provided they remain sterile. For longer term storage, aliquot and freeze to avoid freeze-thaw of the antibody. |
| Gene Symbol: | MNX1 |
| Gene ID: | 3110 |
| Uniprot ID: | MNX1_HUMAN |
| Specificity: | No cross-reactivity reported |
| Immunogen: | Recombinant protein encompassing the C-terminal ~150 amino acids of human HB9/MNX1 |
| Immunogen Sequence: | Human |
| Tissue Specificity | Expressed in lymphoid and pancreatic tissues. |
| Function | Transcription factor. Recognizes and binds to the regulatory elements of target genes, such as visual system homeobox CHX10, negatively modulating transcription. Plays a role in establishing motor neuron identity, in concert with LIM domain transcription factor LMO4. Involved in negatively modulating transcription of interneuron genes in motor neurons, acting, at least in part, by blocking regulatory sequence interactions of the ISL1-LHX3 complex. Involved in pancreas development and function.may play a role in pancreatic cell fate specification. |
| Protein Name | Motor Neuron And Pancreas Homeobox Protein 1Homeobox Protein Hb9 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Motor Neuron And Pancreas Homeobox Protein 1 antibodyAnti-Homeobox Protein Hb9 antibodyAnti-MNX1 antibodyAnti-HLXB9 antibody |
Information sourced from Uniprot.org
