| Short Description : | Rabbit polyclonal MON1A (1-250 aa) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MON1A |
| Gene ID: | 84315 |
| Uniprot ID: | MON1A_HUMAN |
| Immunogen Region: | 1-250 aa |
| Immunogen Sequence: | MHPGGGPSRAERLELGLGRE RPAKAIFLHRRPGEGGGRER CLRCGHVCVRRGPGPREAVP SGRPRPDTLTPPWVRQRAVT GTFCASWTPLRNRRAQRMAT DMQRKRSSECLDGTLTPSDG QSMERAESPTPGMAQGMEPG AGQEGAMFVHARSYEDLTES EDGAASGDSHKEGTRGPPPL PTDMRQISQDFSELSTQLTG VARDLQEEMLPGSSEDWLEP PGAVGRPATEPPREGTTEG |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human MON1A. (Q86VX9). |
| Function | Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes. Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form. |
| Protein Name | Vacuolar Fusion Protein Mon1 Homolog A |
| Database Links | Reactome: R-HSA-8876198 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Vacuolar Fusion Protein Mon1 Homolog A antibodyAnti-MON1A antibodyAnti-SAND1 antibody |
Information sourced from Uniprot.org
