| Host: |
Goat |
| Applications: |
Pep-ELISA/WB/IHC |
| Reactivity: |
Human/Dog/Cow/Pig |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-MOGAT2 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 37kDa band observed in Human Colon, Duodenum and Ileum lysates (calculated MW of 38.2kDa according to NP_079374.2). Recommended concentration: 0.05-0.2µg/ml. Primary incubation |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
MOGAT2 |
| Gene ID: |
80168 |
| Uniprot ID: |
MOGT2_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_079374.2 |
| Immunogen Sequence: |
KESAAHILNRK |
| Function | Involved in glycerolipid synthesis and lipid metabolism. Catalyzes the formation of diacylglycerol, the precursor of triacylglycerol, by transferring the acyl chain of a fatty acyl-CoA to a monoacylglycerol. Plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. Has a preference toward monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0 at sn-2. Able to use 1-monoalkylglycerol (1-MAkG, 1-O-alkylglycerol) as an acyl acceptor for the synthesis of monoalkyl-monoacylglycerol (MAMAG, 1-O-alkyl-3-acylglycerol or 1-O-alkyl-2-acylglycerol) and subsequently, with lower efficiency, may add another acyl chain producing monoalkyl-diacylglycerol (MADAG, 1-O-alkyl-2,3-diacylglycerol). Possesses weak but significant activity with diacylglycerol as substrate, producing triacylglycerol (triacyl-sn-glycerol). |
| Protein Name | 2-Acylglycerol O-Acyltransferase 2Acyl-Coa -Monoacylglycerol Acyltransferase 2Mgat2Hmgat2Diacylglycerol O-Acyltransferase Candidate 5Hdc5Diacylglycerol Acyltransferase 2-Like Protein 5Monoacylglycerol O-Acyltransferase 2 |
| Database Links | Reactome: R-HSA-75109 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinCytoplasmPerinuclear Region |
| Alternative Antibody Names | Anti-2-Acylglycerol O-Acyltransferase 2 antibodyAnti-Acyl-Coa -Monoacylglycerol Acyltransferase 2 antibodyAnti-Mgat2 antibodyAnti-Hmgat2 antibodyAnti-Diacylglycerol O-Acyltransferase Candidate 5 antibodyAnti-Hdc5 antibodyAnti-Diacylglycerol Acyltransferase 2-Like Protein 5 antibodyAnti-Monoacylglycerol O-Acyltransferase 2 antibodyAnti-MOGAT2 antibodyAnti-DC5 antibodyAnti-DGAT2L5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
