| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MOG |
| Gene ID: | 4340 |
| Uniprot ID: | MOG_HUMAN |
| Immunogen Region: | 30-154 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-154 of human Myelin oligodendrocyte glycoprotein (NP_996532.2). |
| Immunogen Sequence: | GQFRVIGPRHPIRALVGDEV ELPCRISPGKNATGMEVGWY RPPFSRVVHLYRNGKDQDGD QAPEYRGRTELLKDAIGEGK VTLRIRNVRFSDEGGFTCFF RDHSYQEEAAMELKVEDPFY WVSPG |
| Tissue Specificity | Found exclusively in the CNS, where it is localized on the surface of myelin and oligodendrocyte cytoplasmic membranes. |
| Function | Mediates homophilic cell-cell adhesion. Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. (Microbial infection) Acts as a receptor for rubella virus. |
| Protein Name | Myelin-Oligodendrocyte Glycoprotein |
| Cellular Localisation | Isoform 1: Cell MembraneMulti-Pass Membrane ProteinIsoform 5: Cell MembraneIsoform 2: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 3: Cell MembraneIsoform 4: Cell MembraneIsoform 6: Cell MembraneIsoform 7: Cell MembraneIsoform 8: Cell MembraneIsoform 9: Cell Membrane |
| Alternative Antibody Names | Anti-Myelin-Oligodendrocyte Glycoprotein antibodyAnti-MOG antibody |
Information sourced from Uniprot.org