Western blot analysis of lysates from HuvEc cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-MMRN2 antibody (133-183 aa) (STJ193664)

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STJ193664
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-Multimerin-2 (133-183 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:MMRN2
Gene ID:79812
Uniprot ID:MMRN2_HUMAN
Immunogen:Synthesized peptide derived from the human MMRN2 at the amino acid range 133-183
Immunogen Region:133-183 aa
Specificity:This antibody detects endogenous levels of MMRN2 at Human/Mouse
Post Translational Modifications N- and O-glycosylated. O-fucosylated within the EMI domain (at Ser-63, Thr-67 and Thr-115) by FUT10/POFUT3 and FUT11/POFUT4. Processed by matrix metalloproteinases (MMPs) including MMP9 and, to a lesser degree, by MMP2 upon angiogenic stimulation.
Function Extracellular matrix protein that plays significant roles in the vascular system and is required for the maintenance and stability of blood vessel. Affects several essential steps in angiogenesis including endothelial cell proliferation, migration, and tube formation. Positively regulates angiogenesis by acting as a ligand for CD93 receptor.
Protein Name Multimerin-2
Emilin-3
Elastin Microfibril Interface Located Protein 3
Elastin Microfibril Interfacer 3
Endoglyx-1 P125/P140 Subunit
Database Links
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Antibody Names Anti-Multimerin-2 antibody
Anti-Emilin-3 antibody
Anti-Elastin Microfibril Interface Located Protein 3 antibody
Anti-Elastin Microfibril Interfacer 3 antibody
Anti-Endoglyx-1 P125/P140 Subunit antibody
Anti-MMRN2 antibody
Anti-EMILIN3 antibody

Information sourced from Uniprot.org

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