Host: |
Rabbit |
Applications: |
IHC/WB |
Reactivity: |
Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-MMP9 (650-700 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Lyophilised |
Purification: |
IgG purified |
Dilution Range: |
IHC, WB (confirmed by recombinant protein). A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
Storage Instruction: |
Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Gene Symbol: |
Mmp9 |
Gene ID: |
17395 |
Uniprot ID: |
MMP9_MOUSE |
Immunogen Region: |
650-700 aa |
Specificity: |
Specific for Matrix Metalloproteinase-9 |
Immunogen: |
A synthetic peptide from aa region 650-700 of mouse MMP9 conjugated to blue carrier protein was used as the antigen. |
Function | Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves NINJ1 to generate the Secreted ninjurin-1 form. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. |
Protein Name | Matrix Metalloproteinase-9Mmp-992 Kda Gelatinase92 Kda Type Iv CollagenaseGelatinase BGelb |
Database Links | Reactome: R-MMU-1433557Reactome: -MMU-1442490Reactome: -MMU-1474228Reactome: -MMU-1592389Reactome: -MMU-2022090Reactome: -MMU-3928665Reactome: -MMU-6798695Reactome: -MMU-9009391 |
Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
Alternative Antibody Names | Anti-Matrix Metalloproteinase-9 antibodyAnti-Mmp-9 antibodyAnti-92 Kda Gelatinase antibodyAnti-92 Kda Type Iv Collagenase antibodyAnti-Gelatinase B antibodyAnti-Gelb antibodyAnti-Mmp9 antibodyAnti-Clg4b antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance