Host: |
Mouse |
Applications: |
WB/FC/ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-Matrix metalloproteinase-9 is suitable for use in Western Blot, Flow Cytometry and ELISA research applications. |
Clonality: |
Monoclonal |
Clone ID: |
5C3 |
Conjugation: |
Unconjugated |
Isotype: |
IgG2a |
Formulation: |
Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000FC 1:200-1:400ELISA 1:10000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
MMP9 |
Gene ID: |
4318 |
Uniprot ID: |
MMP9_HUMAN |
Specificity: |
MMP-9 Monoclonal Antibody detects endogenous levels of MMP-9 protein. |
Immunogen: |
Purified recombinant fragment of human MMP-9 expressed in E. Coli. |
Post Translational Modifications | Processing of the precursor yields different active forms of 64, 67 and 82 kDa. Sequentially processing by MMP3 yields the 82 kDa matrix metalloproteinase-9. N- and O-glycosylated. |
Function | Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves NINJ1 to generate the Secreted ninjurin-1 form. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. |
Protein Name | Matrix Metalloproteinase-9Mmp-992 Kda Gelatinase92 Kda Type Iv CollagenaseGelatinase BGelb Cleaved Into - 67 Kda Matrix Metalloproteinase-9 - 82 Kda Matrix Metalloproteinase-9 |
Database Links | Reactome: R-HSA-1433557Reactome: R-HSA-1442490Reactome: R-HSA-1474228Reactome: R-HSA-1592389Reactome: R-HSA-2022090Reactome: R-HSA-3928665Reactome: R-HSA-6785807Reactome: R-HSA-6798695Reactome: R-HSA-9009391 |
Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
Alternative Antibody Names | Anti-Matrix Metalloproteinase-9 antibodyAnti-Mmp-9 antibodyAnti-92 Kda Gelatinase antibodyAnti-92 Kda Type Iv Collagenase antibodyAnti-Gelatinase B antibodyAnti-Gelb Cleaved Into - 67 Kda Matrix Metalloproteinase-9 - 82 Kda Matrix Metalloproteinase-9 antibodyAnti-MMP9 antibodyAnti-CLG4B antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance