Anti-MMADHC antibody (STJA0008663)

SKU:
STJA0008663
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Cobalamin trafficking protein CblD is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MMADHC
Gene ID: 27249
Uniprot ID: MMAD_HUMAN
Specificity: This antibody detects endogenous levels of MMADHC at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human MMADHC
Function Involved in cobalamin metabolism and trafficking. Plays a role in regulating the biosynthesis and the proportion of two coenzymes, methylcob(III)alamin (MeCbl) and 5'-deoxyadenosylcobalamin (AdoCbl). Promotes oxidation of cob(II)alamin bound to MMACHC. The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR (methionine synthase) which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine.
Protein Name Cobalamin Trafficking Protein Cbld
Cbld
Methylmalonic Aciduria And Homocystinuria Type D Protein - Mitochondrial
Database Links Reactome: R-HSA-3359473
Reactome: R-HSA-9759218
Cellular Localisation Cytoplasm
Mitochondrion
Alternative Antibody Names Anti-Cobalamin Trafficking Protein Cbld antibody
Anti-Cbld antibody
Anti-Methylmalonic Aciduria And Homocystinuria Type D Protein - Mitochondrial antibody
Anti-MMADHC antibody
Anti-C2orf25 antibody
Anti-CL25022 antibody
Anti-HSPC161 antibody
Anti-My011 antibody

Information sourced from Uniprot.org

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