| Host: |
Goat |
| Applications: |
Pep-ELISA/IHC |
| Reactivity: |
Human/Mouse/Rat/Dog/Cow |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-MLX (Internal) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
IHC-Recommended concentration, 2.5-3.8µg/mlELISA-antibody detection limit dilution 1:128000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
MLX |
| Gene ID: |
6945 |
| Uniprot ID: |
MLX_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_937848.1; NP_937847.1; NP_733752.1 |
| Specificity: |
This antibody is expected to recognize all three reported isoforms (NP_937848.1; NP_937847.1; NP_733752.1). |
| Immunogen Sequence: |
QIVKAHQDNPHEGED |
| Function | Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MAD1, MAD4, MNT, WBSCR14 and MLXIP which recognizes the core sequence 5'-CACGTG-3'. The TCFL4-MAD1, TCFL4-MAD4, TCFL4-WBSCR14 complexes are transcriptional repressors. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation. |
| Protein Name | Max-Like Protein XClass D Basic Helix-Loop-Helix Protein 13Bhlhd13Max-Like Bhlhzip ProteinProtein BigmaxTranscription Factor-Like Protein 4 |
| Database Links | Reactome: R-HSA-163765 |
| Cellular Localisation | Isoform Alpha: CytoplasmFound Predominantly In The CytoplasmIsoform Beta: CytoplasmIsoform Gamma: NucleusFound Predominantly In The Nucleus |
| Alternative Antibody Names | Anti-Max-Like Protein X antibodyAnti-Class D Basic Helix-Loop-Helix Protein 13 antibodyAnti-Bhlhd13 antibodyAnti-Max-Like Bhlhzip Protein antibodyAnti-Protein Bigmax antibodyAnti-Transcription Factor-Like Protein 4 antibodyAnti-MLX antibodyAnti-BHLHD13 antibodyAnti-TCFL4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
