Anti-MLX antibody (111-160) (STJ94156)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from human Mlx. AA range:111-160
General Information
| Short Description | Rabbit polyclonal anti-Max-like protein X (111-160) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MLX |
| Gene ID | 6945 |
| Uniprot ID | MLX_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Mlx. AA range:111-160 |
| Immunogen Region | 111-160 |
| Specificity | Mlx Polyclonal Antibody detects endogenous levels of Mlx protein. |
Additional Info
| Tissue Specificity | Expressed in all tissues tested, including spleen, thymus, prostate, ovary, intestine, colon, peripheral blood leukocyte, heart, liver, skeletal muscle and kidney. Lower levels of expression in testis, brain, placenta and lung. |
| Function | Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MAD1, MAD4, MNT, WBSCR14 and MLXIP which recognizes the core sequence 5'-CACGTG-3'. The TCFL4-MAD1, TCFL4-MAD4, TCFL4-WBSCR14 complexes are transcriptional repressors. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation. |
| Protein Name | Max-Like Protein XClass D Basic Helix-Loop-Helix Protein 13Bhlhd13Max-Like Bhlhzip ProteinProtein BigmaxTranscription Factor-Like Protein 4 |
| Database Links | Reactome: R-HSA-163765 |
| Cellular Localisation | Isoform Alpha: CytoplasmFound Predominantly In The CytoplasmIsoform Beta: CytoplasmIsoform Gamma: NucleusFound Predominantly In The Nucleus |
| Alternative Antibody Names | Anti-Max-Like Protein X antibodyAnti-Class D Basic Helix-Loop-Helix Protein 13 antibodyAnti-Bhlhd13 antibodyAnti-Max-Like Bhlhzip Protein antibodyAnti-Protein Bigmax antibodyAnti-Transcription Factor-Like Protein 4 antibodyAnti-MLX antibodyAnti-BHLHD13 antibodyAnti-TCFL4 antibody |
Information sourced from Uniprot.org