| Tissue Specificity | Expressed in all tissues tested, including spleen, thymus, prostate, ovary, intestine, colon, peripheral blood leukocyte, heart, liver, skeletal muscle and kidney. Lower levels of expression in testis, brain, placenta and lung. |
| Function | Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MAD1, MAD4, MNT, WBSCR14 and MLXIP which recognizes the core sequence 5'-CACGTG-3'. The TCFL4-MAD1, TCFL4-MAD4, TCFL4-WBSCR14 complexes are transcriptional repressors. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation. |
| Protein Name | Max-Like Protein XClass D Basic Helix-Loop-Helix Protein 13Bhlhd13Max-Like Bhlhzip ProteinProtein BigmaxTranscription Factor-Like Protein 4 |
| Database Links | Reactome: R-HSA-163765 |
| Cellular Localisation | Isoform Alpha: CytoplasmFound Predominantly In The CytoplasmIsoform Beta: CytoplasmIsoform Gamma: NucleusFound Predominantly In The Nucleus |
| Alternative Antibody Names | Anti-Max-Like Protein X antibodyAnti-Class D Basic Helix-Loop-Helix Protein 13 antibodyAnti-Bhlhd13 antibodyAnti-Max-Like Bhlhzip Protein antibodyAnti-Protein Bigmax antibodyAnti-Transcription Factor-Like Protein 4 antibodyAnti-MLX antibodyAnti-BHLHD13 antibodyAnti-TCFL4 antibody |
Information sourced from Uniprot.org
