| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-E3 ubiquitin-protein ligase makorin-2 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MKRN2 |
| Gene ID: | 23609 |
| Uniprot ID: | MKRN2_HUMAN |
| Specificity: | This antibody detects endogenous levels of MKRN2 at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human MKRN2 |
| Function | E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Promotes the polyubiquitination and proteasome-dependent degradation of RELA/p65, thereby suppressing RELA-mediated NF-kappaB transactivation and negatively regulating inflammatory responses. Plays a role in the regulation of spermiation and in male fertility. |
| Protein Name | E3 Ubiquitin-Protein Ligase Makorin-2Ring Finger Protein 62Ring-Type E3 Ubiquitin Transferase Makorin-2 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Makorin-2 antibodyAnti-Ring Finger Protein 62 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Makorin-2 antibodyAnti-MKRN2 antibodyAnti-RNF62 antibodyAnti-HSPC070 antibody |
Information sourced from Uniprot.org