Name: Anti-MKP1 antibody (1-172 aa) (STJ11105073)
SKU: STJ11105073
Availability: InStock

Anti-MKP1 antibody (1-172 aa) (STJ11105073)

SKU:

STJ11105073

£112.50 - £524.50

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality :	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification:	Affinity purification
Concentration:	Lot specific
Dilution Range:	WB:1:1000-1:5000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	Dusp1
Gene ID:	19252
Uniprot ID:	DUS1_MOUSE
Immunogen Region:	1-172 aa
Specificity:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of mouse MKP1. (NP_038670.1).
Immunogen Sequence:	MVMEVGILDAGGLRALLREG AAQCLLLDCRSFFAFNAGHI AGSVNVRFSTIVRRRAKGAM GLEHIVPNAELRGRLLAGAY HAVVLLDERSASLDGAKRDG TLALAAGALCREARSTQVFF LQGGYEAFSASCPELCSKQS TPTGLSLPLSTSVPDSAESG CSSCSTPLYDQG

Post Translational Modifications	Phosphorylation at Ser-359 and Ser-364 by MAPK1/ERK2 and MAPK3/ERK1 reduces its rate of degradation. 'Lys-48'-linked polyubiquitinated by NEURL3, leading to proteasomal degradation.
Function	Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.
Protein Name	Dual Specificity Protein Phosphatase 1 Mitogen-Activated Protein Kinase Phosphatase 1 Map Kinase Phosphatase 1 Mkp-1 Protein-Tyrosine Phosphatase 3ch134 Protein-Tyrosine Phosphatase Erp
Database Links	Reactome: R-MMU-112409 Reactome: -MMU-5675221
Cellular Localisation	Nucleus
Alternative Antibody Names	Anti-Dual Specificity Protein Phosphatase 1 antibody Anti-Mitogen-Activated Protein Kinase Phosphatase 1 antibody Anti-Map Kinase Phosphatase 1 antibody Anti-Mkp-1 antibody Anti-Protein-Tyrosine Phosphatase 3ch134 antibody Anti-Protein-Tyrosine Phosphatase Erp antibody Anti-Dusp1 antibody Anti-3ch134 antibody Anti-Mkp1 antibody Anti-Ptpn10 antibody Anti-Ptpn16 antibody

Information sourced from Uniprot.org

Anti-MKP1 antibody (1-172 aa) (STJ11105073)

General Information

Model	Name	Host	Clonality	Reactivity	Application
STJ11103914	Anti-OsELF3 antibody (1-172 aa) (STJ11103914)	Rabbit	Polyclonal	O.sativa	WB/ELISA
STJ193880	Anti-BIRC8 antibody (122-172 aa) (STJ193880)	Rabbit	Polyclonal	Human/Rat/Mouse	WB
STJ194583	Anti-TPRKB antibody (122-172 aa) (STJ194583)	Rabbit	Polyclonal	Human/Mouse/Rat	WB
STJ195806	Anti-PTF1A antibody (172-222 aa) (STJ195806)	Rabbit	Polyclonal	Human/Mouse/Rat	WB/IHC
STJ195907	Anti-SHMT2 antibody (122-172 aa) (STJ195907)	Rabbit	Polyclonal	Human/Rat/Mouse	WB