Anti-MKP1 antibody (1-172 aa) (STJ11105073)

Anti-MKP1 antibody (1-172 aa) (STJ11105073)

SKU:
STJ11105073
$152.49 - $697.59
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Applications:WB/ELISA
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:1000-1:5000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:Dusp1
Gene ID:19252
Uniprot ID:DUS1_MOUSE
Immunogen Region:1-172 aa
Immunogen Sequence:MVMEVGILDAGGLRALLREG AAQCLLLDCRSFFAFNAGHI AGSVNVRFSTIVRRRAKGAM GLEHIVPNAELRGRLLAGAY HAVVLLDERSASLDGAKRDG TLALAAGALCREARSTQVFF LQGGYEAFSASCPELCSKQS TPTGLSLPLSTSVPDSAESG CSSCSTPLYDQG
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of mouse MKP1. (NP_038670.1).
Post Translational Modifications Phosphorylation at Ser-359 and Ser-364 by MAPK1/ERK2 and MAPK3/ERK1 reduces its rate of degradation. 'Lys-48'-linked polyubiquitinated by NEURL3, leading to proteasomal degradation.
Function Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.
Protein Name Dual Specificity Protein Phosphatase 1
Mitogen-Activated Protein Kinase Phosphatase 1
Map Kinase Phosphatase 1
Mkp-1
Protein-Tyrosine Phosphatase 3ch134
Protein-Tyrosine Phosphatase Erp
Database Links Reactome: R-MMU-112409
Reactome: -MMU-5675221
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Dual Specificity Protein Phosphatase 1 antibody
Anti-Mitogen-Activated Protein Kinase Phosphatase 1 antibody
Anti-Map Kinase Phosphatase 1 antibody
Anti-Mkp-1 antibody
Anti-Protein-Tyrosine Phosphatase 3ch134 antibody
Anti-Protein-Tyrosine Phosphatase Erp antibody
Anti-Dusp1 antibody
Anti-3ch134 antibody
Anti-Mkp1 antibody
Anti-Ptpn10 antibody
Anti-Ptpn16 antibody

Information sourced from Uniprot.org

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