Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Multiple inositol polyphosphate phosphatase 1-tetrakisphosphate 3-phosphataseP4 3-phosphatase (328-377 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
MINPP1 |
Gene ID: |
9562 |
Uniprot ID: |
MINP1_HUMAN |
Immunogen Region: |
328-377 aa |
Specificity: |
MIPP Polyclonal Antibody detects endogenous levels of MIPP protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human MINPP1 at the amino acid range 328-377 |
Function | Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification). May play a role in the transition of chondrocytes from proliferation to hypertrophy. Through the regulation of intracellular inositol polyphosphates, may control intracellular cation homeostasis, including that of calcium and iron, hence affecting free cation availability required for neural cell signaling. |
Protein Name | Multiple Inositol Polyphosphate Phosphatase 12 -3-Bisphosphoglycerate 3-Phosphatase2 -3-Bpg PhosphataseInositol1 -3 -4 -5-Tetrakisphosphate 3-PhosphataseIns(1 -3 -4 -5p(4 3-Phosphatase |
Database Links | Reactome: R-HSA-1855231 |
Cellular Localisation | Endoplasmic Reticulum Lumen |
Alternative Antibody Names | Anti-Multiple Inositol Polyphosphate Phosphatase 1 antibodyAnti-2 -3-Bisphosphoglycerate 3-Phosphatase antibodyAnti-2 -3-Bpg Phosphatase antibodyAnti-Inositol antibodyAnti-1 -3 -4 -5-Tetrakisphosphate 3-Phosphatase antibodyAnti-Ins(1 -3 -4 -5p(4 3-Phosphatase antibodyAnti-MINPP1 antibodyAnti-MIPP antibodyAnti-UNQ900 antibodyAnti-PRO1917 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance