| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MIER1 (110-160) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MIER1 |
| Gene ID: |
57708 |
| Uniprot ID: |
MIER1_HUMAN |
| Immunogen Region: |
110-160 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 110-160 of human MIER1 (Q8N108). |
| Immunogen Sequence: |
SGENKEENIKDSSGQEDETQ SSNDDPSQSVASQDAQEIIR PRRCKYFDTNS |
| Tissue Specificity | Ubiquitously expressed, but at very low levels. However, consistent level of expression are observed in heart, testis, thyroid, ovary and adrenal gland. Transcripts are up-regulated in breast carcinoma cell lines and tumor. |
| Function | Transcriptional repressor regulating the expression of a number of genes including SP1 target genes. Probably functions through recruitment of HDAC1 a histone deacetylase involved in chromatin silencing. |
| Protein Name | Mesoderm Induction Early Response Protein 1Early Response 1Er1Mi-Er1Hmi-Er1 |
| Cellular Localisation | Isoform 1: NucleusIsoform 2: NucleusIsoform 3: NucleusIsoform 4: CytoplasmIsoform 5: CytoplasmIsoform 6: Cytoplasm |
| Alternative Antibody Names | Anti-Mesoderm Induction Early Response Protein 1 antibodyAnti-Early Response 1 antibodyAnti-Er1 antibodyAnti-Mi-Er1 antibodyAnti-Hmi-Er1 antibodyAnti-MIER1 antibodyAnti-KIAA1610 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
