| Tissue Specificity | Among normal tissues, present only in Leydig cells. Strongly up-regulated in breast cancers and in brain cancer distant metastasis (at protein level). Up-regulated in prostate cancer cells and in the higher grades of prostate adenocarcinoma (at protein level). |
| Post Translational Modifications | Isoprenylation facilitates association with the plasma membrane and enhances the migratory phenotype of cells by inducing increased filopodia formation. |
| Function | Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process. |
| Protein Name | Migration And Invasion Enhancer 1Hbv X-Transactivated Gene 4 ProteinHbv Xag-Transactivated Protein 4Protein C35 |
| Cellular Localisation | CytoplasmCytosolCell MembraneLipid-AnchorCytoplasmic SideConcentrates At The Leading Edge Of Migrating CellsLocalizes Outside Membrane Raft Regions |
| Alternative Antibody Names | Anti-Migration And Invasion Enhancer 1 antibodyAnti-Hbv X-Transactivated Gene 4 Protein antibodyAnti-Hbv Xag-Transactivated Protein 4 antibodyAnti-Protein C35 antibodyAnti-MIEN1 antibodyAnti-C17orf37 antibodyAnti-RDX12 antibodyAnti-XTP4 antibody |
Information sourced from Uniprot.org
