| Tissue Specificity | Expressed in heart, adrenal gland, testis, liver, brain and fetal brain. Not expressed in pancreas. |
| Function | Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity). |
| Protein Name | Alpha-1 -3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase CN-Acetylglucosaminyltransferase Iv HomologHgnt-Iv-HN-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase IvcGlcnac-T IvcGnt-IvcN-Acetylglucosaminyltransferase IvcUdp-N-Acetylglucosamine - Alpha-1 -3-D-Mannoside Beta-1 -4-N-Acetylglucosaminyltransferase Ivc |
| Database Links | Reactome: R-HSA-9694548Reactome: R-HSA-975577 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Alpha-1 -3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase C antibodyAnti-N-Acetylglucosaminyltransferase Iv Homolog antibodyAnti-Hgnt-Iv-H antibodyAnti-N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase Ivc antibodyAnti-Glcnac-T Ivc antibodyAnti-Gnt-Ivc antibodyAnti-N-Acetylglucosaminyltransferase Ivc antibodyAnti-Udp-N-Acetylglucosamine - Alpha-1 -3-D-Mannoside Beta-1 -4-N-Acetylglucosaminyltransferase Ivc antibodyAnti-MGAT4C antibody |
Information sourced from Uniprot.org
