| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MGAT4C (299-478) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MGAT4C |
| Gene ID: |
25834 |
| Uniprot ID: |
MGT4C_HUMAN |
| Immunogen Region: |
299-478 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 299-478 of human MGAT4C (NP_037376.2). |
| Immunogen Sequence: |
KNVIRFKPSLFQHMGYYSSY KGTENKLKDDDFEEESFDIP DNPPASLYTNMNVFENYEAS KAYSSVDEYFWGKPPSTGDV FVIVFENPIIIKKIKVNTGT EDRQNDILHHGALDVGENVM PSKQRRQCSTYLRLGEFKNG NFEMSGVNQKIPFDIHCMRI YVTKTQKEWLIIRSISIWTS |
| Tissue Specificity | Expressed in heart, adrenal gland, testis, liver, brain and fetal brain. Not expressed in pancreas. |
| Function | Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Does not catalyze the transfer of GlcNAc to the Manalpha1-6 arm to form GlcNAcBeta1-4Manalpha1-6 linkage ('GnT-VI' activity). |
| Protein Name | Alpha-1 -3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase CN-Acetylglucosaminyltransferase Iv HomologHgnt-Iv-HN-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase IvcGlcnac-T IvcGnt-IvcN-Acetylglucosaminyltransferase IvcUdp-N-Acetylglucosamine - Alpha-1 -3-D-Mannoside Beta-1 -4-N-Acetylglucosaminyltransferase Ivc |
| Database Links | Reactome: R-HSA-9694548Reactome: R-HSA-975577 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Alpha-1 -3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase C antibodyAnti-N-Acetylglucosaminyltransferase Iv Homolog antibodyAnti-Hgnt-Iv-H antibodyAnti-N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase Ivc antibodyAnti-Glcnac-T Ivc antibodyAnti-Gnt-Ivc antibodyAnti-N-Acetylglucosaminyltransferase Ivc antibodyAnti-Udp-N-Acetylglucosamine - Alpha-1 -3-D-Mannoside Beta-1 -4-N-Acetylglucosaminyltransferase Ivc antibodyAnti-MGAT4C antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
