| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-RNA-binding protein MEX3B (434-484 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MEX3B |
| Gene ID: | 84206 |
| Uniprot ID: | MEX3B_HUMAN |
| Immunogen Region: | 434-484 aa |
| Specificity: | This antibody detects endogenous levels of MEX3B at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human MEX3B at the amino acid range 434-484 |
| Post Translational Modifications | Phosphorylation at Ser-462 creates a docking site for 14-3-3, which stabilizes the protein and modulates its ability to bind RNA. |
| Function | RNA-binding protein. May be involved in post-transcriptional regulatory mechanisms. |
| Protein Name | Rna-Binding Protein Mex3bRing Finger And Kh Domain-Containing Protein 3Ring Finger Protein 195 |
| Cellular Localisation | NucleusCytoplasmP-BodyCytoplasmic GranulePredominantly Expressed In The Cytoplasm And Shuttles Between The Cytoplasm And The Nucleus Through The Crm1 Export PathwayLocalization To P-Bodies Is Dependent On 14-3-3 |
| Alternative Antibody Names | Anti-Rna-Binding Protein Mex3b antibodyAnti-Ring Finger And Kh Domain-Containing Protein 3 antibodyAnti-Ring Finger Protein 195 antibodyAnti-MEX3B antibodyAnti-KIAA2009 antibodyAnti-RKHD3 antibodyAnti-RNF195 antibody |
Information sourced from Uniprot.org