| Function | Protein-histidine N-methyltransferase that specifically catalyzes 1-methylhistidine (pros-methylhistidine) methylation of target proteins. Specifically methylates the second His of proteins with a His-x-His (HxH) motif (where 'x' is preferably a small amino acid), while exploiting the first one as a recognition signature. Catalyzes methylation of target proteins such as S100A9, NDUFB3, SLC39A5, SLC39A7, ARMC6 and DNAJB12.1-methylhistidine modification may affect the binding of zinc and other metals to its target proteins. Constitutes the main methyltransferase for the 1-methylhistidine modification in cell. |
| Protein Name | Protein-L-Histidine N-Pros-MethyltransferaseDora Reverse Strand ProteinDrevDrev1Methyltransferase-Like Protein 9Hmettl9 |
| Cellular Localisation | Endoplasmic ReticulumMitochondrionColocalizes With Membranous Compartments Such As The Endoplasmic Reticulum And Mitochondria |
| Alternative Antibody Names | Anti-Protein-L-Histidine N-Pros-Methyltransferase antibodyAnti-Dora Reverse Strand Protein antibodyAnti-Drev antibodyAnti-Drev1 antibodyAnti-Methyltransferase-Like Protein 9 antibodyAnti-Hmettl9 antibodyAnti-METTL9 antibodyAnti-DREV antibodyAnti-CGI-81 antibody |
Information sourced from Uniprot.org
