| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-rRNA N6-adenosine-methyltransferase METTL5 (59-109) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | METTL5 |
| Gene ID: | 29081 |
| Uniprot ID: | METL5_HUMAN |
| Immunogen Region: | 59-109 |
| Specificity: | This antibody detects endogenous levels of human METL5 |
| Immunogen: | Synthesized peptide derived from human METL5 AA range: 59-109 |
| Function | Catalytic subunit of a heterodimer with TRMT112, which specifically methylates the 6th position of adenine in position 1832 of 18S rRNA. N6-methylation of adenine(1832) in 18S rRNA resides in the decoding center of 18S rRNA and is required for translation and embryonic stem cells (ESCs) pluripotency and differentiation. |
| Protein Name | Rrna N(6-Adenosine-Methyltransferase Mettl5Methyltransferase-Like Protein 5 |
| Cellular Localisation | NucleusPresynapsePostsynapse |
| Alternative Antibody Names | Anti-Rrna N(6-Adenosine-Methyltransferase Mettl5 antibodyAnti-Methyltransferase-Like Protein 5 antibodyAnti-METTL5 antibodyAnti-DC3 antibodyAnti-HSPC133 antibody |
Information sourced from Uniprot.org