| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Histidine protein methyltransferase 1 homolog is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | METTL18 |
| Gene ID: | 92342 |
| Uniprot ID: | MET18_HUMAN |
| Specificity: | This antibody detects endogenous levels of C1orf156 at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human C1orf156 |
| Function | Protein-L-histidine N-tele-methyltransferase that specifically monomethylates RPL3, thereby regulating translation elongation. Histidine methylation of RPL3 regulates translation elongation by slowing ribosome traversal on tyrosine codons: slower elongation provides enough time for proper folding of synthesized proteins and prevents cellular aggregation of tyrosine-rich proteins. |
| Protein Name | Histidine Protein Methyltransferase 1 HomologArsenic-Transactivated Protein 2Astp2Methyltransferase-Like Protein 18 |
| Cellular Localisation | CytoplasmCytosolNucleusNucleolus |
| Alternative Antibody Names | Anti-Histidine Protein Methyltransferase 1 Homolog antibodyAnti-Arsenic-Transactivated Protein 2 antibodyAnti-Astp2 antibodyAnti-Methyltransferase-Like Protein 18 antibodyAnti-METTL18 antibodyAnti-ASTP2 antibodyAnti-C1orf156 antibody |
Information sourced from Uniprot.org