| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | METTL13 |
| Gene ID: | 51603 |
| Uniprot ID: | EFNMT_HUMAN |
| Immunogen Region: | 540-699 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 540-699 of human METTL13 (NP_057019.3). |
| Immunogen Sequence: | SQSDRMKVHIADGLDYIASL AGGGEARPCYDVIMFDVDSK DPTLGMSCPPPAFVEQSFLQ KVKSILTPEGVFILNLVCRD LGLKDSVLAGLKAVFPLLYV RRIEGEVNEILFCQLHPEQK LATPELLETAQALERTLRKP GRGWDDTYVLSDMLKTVKIV |
| Function | Dual methyltransferase that catalyzes methylation of elongation factor 1-alpha (EEF1A1 and EEF1A2) at two different positions, and is therefore involved in the regulation of mRNA translation. Via its C-terminus, methylates EEF1A1 and EEF1A2 at the N-terminal residue 'Gly-2'. Via its N-terminus dimethylates EEF1A1 and EEF1A2 at residue 'Lys-55'. Has no activity towards core histones H2A, H2B, H3 and H4. |
| Protein Name | Eef1a Lysine And N-Terminal MethyltransferaseEef1a-KnmtMethyltransferase-Like Protein 13 Includes - Eef1a Lysine Methyltransferase - Eef1a N-Terminal Methyltransferase |
| Cellular Localisation | CytoplasmNucleusMitochondrion |
| Alternative Antibody Names | Anti-Eef1a Lysine And N-Terminal Methyltransferase antibodyAnti-Eef1a-Knmt antibodyAnti-Methyltransferase-Like Protein 13 Includes - Eef1a Lysine Methyltransferase - Eef1a N-Terminal Methyltransferase antibodyAnti-METTL13 antibodyAnti-EEF1AKNMT antibodyAnti-FEAT antibodyAnti-KIAA0859 antibodyAnti-CGI-01 antibody |
Information sourced from Uniprot.org