Anti-METAP1D antibody (STJA0004512)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenFusion protein of human METAP1D
General Information
| Short Description | Rabbit polyclonal anti-Methionine Aminopeptidase 1d-Mitochondrial for use in WB, IHC and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.9 mg/mL |
| Purification | Antigen affinity purification |
| Dilution Range | WB 1:500-1:2000, IHC 1:40-1:200 |
| Formulation | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | METAP1D |
| Gene ID | 254042 |
| Uniprot ID | MAP12_HUMAN |
| Immunogen | Fusion protein of human METAP1D |
Additional Info
| Tissue Specificity | Overexpressed in colon cancer cell lines and colon tumors as compared to normal tissues (at protein level). |
| Function | Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. May play a role in colon tumorigenesis. |
| Protein Name | Methionine Aminopeptidase 1d - MitochondrialMap 1dMetap 1dMethionyl Aminopeptidase Type 1d - MitochondrialPeptidase M 1d |
| Database Links | |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Methionine Aminopeptidase 1d - Mitochondrial antibodyAnti-Map 1d antibodyAnti-Metap 1d antibodyAnti-Methionyl Aminopeptidase Type 1d - Mitochondrial antibodyAnti-Peptidase M 1d antibodyAnti-METAP1D antibodyAnti-MAP1D antibody |
Information sourced from Uniprot.org