| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Homeobox protein MOX-2 (151-200) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MEOX2 |
| Gene ID: | 4223 |
| Uniprot ID: | MEOX2_HUMAN |
| Immunogen Region: | 151-200 |
| Specificity: | MOX-2 Polyclonal Antibody detects endogenous levels of MOX-2 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human MEOX2. AA range:151-200 |
| Function | Mesodermal transcription factor that plays a key role in somitogenesis and somitogenesis and limb muscle differentiation. Required during limb development for normal appendicular muscle formation and for the normal regulation of myogenic genes. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle. Also acts as a negative regulator of angiogenesis. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Together with TCF15, regulates transcription in heart endothelial cells to regulate fatty acid transport across heart endothelial cells. |
| Protein Name | Homeobox Protein Mox-2Growth Arrest-Specific HomeoboxMesenchyme Homeobox 2 |
| Cellular Localisation | NucleusNucleus Speckle |
| Alternative Antibody Names | Anti-Homeobox Protein Mox-2 antibodyAnti-Growth Arrest-Specific Homeobox antibodyAnti-Mesenchyme Homeobox 2 antibodyAnti-MEOX2 antibodyAnti-GAX antibodyAnti-MOX2 antibody |
Information sourced from Uniprot.org