| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Meiosis-specific coiled-coil domain-containing protein MEIOC (218-268 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MEIOC |
| Gene ID: |
284071 |
| Uniprot ID: |
MEIOC_HUMAN |
| Immunogen Region: |
218-268 aa |
| Specificity: |
This antibody detects endogenous levels of CQ104 at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human CQ104 at the amino acid range 218-268 |
| Function | Is required for meiosis completion in both male and female germ cells. Confers stability to numerous meiotic mRNAs in gonads allowing proper initiation and progression into meiosis prophase I. The function may involve YTHDC2 and is independent of induction by retinoic acid (RA). Maintains an extended meiotic prophase I by properly promoting the transition from a mitotic to a meiotic cell cycle program by binding transcripts through its interaction with YTHDC2 that regulate the mitotic cell cycle. |
| Protein Name | Meiosis-Specific Coiled-Coil Domain-Containing Protein MeiocMeiosis-Specific With Coiled-Coil Domain Protein |
| Cellular Localisation | CytoplasmNucleusAt Late Pachytene A Fraction Is Nuclear |
| Alternative Antibody Names | Anti-Meiosis-Specific Coiled-Coil Domain-Containing Protein Meioc antibodyAnti-Meiosis-Specific With Coiled-Coil Domain Protein antibodyAnti-MEIOC antibodyAnti-C17orf104 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
