Host: |
Rabbit |
Applications: |
IHC/IF/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Myocyte-specific enhancer factor 2D (410-459 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
MEF2D |
Gene ID: |
4209 |
Uniprot ID: |
MEF2D_HUMAN |
Immunogen Region: |
410-459 aa |
Specificity: |
MEF-2D Polyclonal Antibody detects endogenous levels of MEF-2D protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human MEF2D at the amino acid range 410-459 |
Function | Transcriptional activator which binds specifically to the MEF2 element, 5'-YTAAT(4)TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis. |
Protein Name | Myocyte-Specific Enhancer Factor 2d |
Database Links | Reactome: R-HSA-2151201Reactome: R-HSA-400253Reactome: R-HSA-525793Reactome: R-HSA-9031628Reactome: R-HSA-9707616 |
Cellular Localisation | NucleusTranslocated By Hdac4 To Nuclear Dots |
Alternative Antibody Names | Anti-Myocyte-Specific Enhancer Factor 2d antibodyAnti-MEF2D antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance