Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-MED26 (500-574) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
MED26 |
Gene ID: |
9441 |
Uniprot ID: |
MED26_HUMAN |
Immunogen Region: |
500-574 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 500-574 of human MED26 (NP_004822.2). |
Immunogen Sequence: |
SGAQTPGAHHFMSEYLKQEE STRQGARQLHVLVPQSPPTD LPGLTREVTQDDLDRIQASQ WPGVNGCQDTQGNWY |
Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors. |
Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 26Activator-Recruited Cofactor 70 Kda ComponentArc70Cofactor Required For Sp1 Transcriptional Activation Subunit 7Crsp Complex Subunit 7Mediator Complex Subunit 26Transcriptional Coactivator Crsp70 |
Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-212436Reactome: R-HSA-381340 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 26 antibodyAnti-Activator-Recruited Cofactor 70 Kda Component antibodyAnti-Arc70 antibodyAnti-Cofactor Required For Sp1 Transcriptional Activation Subunit 7 antibodyAnti-Crsp Complex Subunit 7 antibodyAnti-Mediator Complex Subunit 26 antibodyAnti-Transcriptional Coactivator Crsp70 antibodyAnti-MED26 antibodyAnti-ARC70 antibodyAnti-CRSP7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance