Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors. |
Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 26Activator-Recruited Cofactor 70 Kda ComponentArc70Cofactor Required For Sp1 Transcriptional Activation Subunit 7Crsp Complex Subunit 7Mediator Complex Subunit 26Transcriptional Coactivator Crsp70 |
Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-212436Reactome: R-HSA-381340Reactome: R-HSA-9833110 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 26 antibodyAnti-Activator-Recruited Cofactor 70 Kda Component antibodyAnti-Arc70 antibodyAnti-Cofactor Required For Sp1 Transcriptional Activation Subunit 7 antibodyAnti-Crsp Complex Subunit 7 antibodyAnti-Mediator Complex Subunit 26 antibodyAnti-Transcriptional Coactivator Crsp70 antibodyAnti-MED26 antibodyAnti-ARC70 antibodyAnti-CRSP7 antibody |
Information sourced from Uniprot.org