| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors. Also required for transcriptional activation subsequent to the assembly of the pre-initiation complex. Required for transcriptional activation by adenovirus E1A protein. Required for ELK1-dependent transcriptional activation in response to activated Ras signaling. |
| Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 23Cofactor Required For Sp1 Transcriptional Activation Subunit 3Crsp Complex Subunit 3Mediator Complex Subunit 23Protein Sur-2 HomologMsur-2 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 23 antibodyAnti-Cofactor Required For Sp1 Transcriptional Activation Subunit 3 antibodyAnti-Crsp Complex Subunit 3 antibodyAnti-Mediator Complex Subunit 23 antibodyAnti-Protein Sur-2 Homolog antibodyAnti-Msur-2 antibodyAnti-Med23 antibodyAnti-Crsp3 antibodyAnti-Kiaa1216 antibodyAnti-Sur2 antibody |
Information sourced from Uniprot.org
