| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MDH2 |
| Gene ID: | 4191 |
| Uniprot ID: | MDHM_HUMAN |
| Immunogen Region: | 59-338 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 59-338 of human MDH2 (NP_005909.2). |
| Immunogen Sequence: | AHTPGVAADLSHIETKAAVK GYLGPEQLPDCLKGCDVVVI PAGVPRKPGMTRDDLFNTNA TIVATLTAACAQHCPEAMIC VIANPVNSTIPITAEVFKKH GVYNPNKIFGVTTLDIVRAN TFVAELKGLDPARVNVPVIG GHAGKTIIPLISQCTPKVDF PQDQLTALTGRIQEAGTEVV KAKAGAGSATLSMAYAGARF VFSLVDAMNGKEGVVECSFV KSQETECTYFSTPLLLGKK |
| Post Translational Modifications | Acetylation is enhanced by up to 67% after treatment either with trichostin A (TSA) or with nicotinamide (NAM) with the appearance of tri- and tetraacetylations. Glucose also increases acetylation by about 60%. |
| Protein Name | Malate Dehydrogenase - Mitochondrial |
| Database Links | Reactome: R-HSA-71403Reactome: R-HSA-9837999Reactome: R-HSA-9856872 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Malate Dehydrogenase - Mitochondrial antibodyAnti-MDH2 antibody |
Information sourced from Uniprot.org
