Anti-MCCC1 antibody (640-725) (STJ112060)

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STJ112060
£112.50 - £524.50
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Host: Rabbit
Applications: WB/IHC-P/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:1000-1:5000
IHC-P:1:50-1:100
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MCCC1
Gene ID: 56922
Uniprot ID: MCCA_HUMAN
Immunogen Region: 640-725
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 640-725 of human MCCC1 (NP_064551.3).
Immunogen Sequence: VSSQETQGGPLAPMTGTIEK VFVKAGDKVKAGDSLMVMIA MKMEHTIKSPKDGTVKKVFY REGAQANRHTPLVEFEEEES DKRESE
Post Translational Modifications Acetylated.
Function Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism.
Protein Name Methylcrotonoyl-Coa Carboxylase Subunit Alpha - Mitochondrial
Mccase Subunit Alpha
3-Methylcrotonyl-Coa Carboxylase 1
3-Methylcrotonyl-Coa Carboxylase Biotin-Containing Subunit
3-Methylcrotonyl-Coa -Carbon Dioxide Ligase Subunit Alpha
Database Links Reactome: R-HSA-196780
Reactome: R-HSA-3371599
Reactome: R-HSA-70895
Cellular Localisation Mitochondrion Matrix
Alternative Antibody Names Anti-Methylcrotonoyl-Coa Carboxylase Subunit Alpha - Mitochondrial antibody
Anti-Mccase Subunit Alpha antibody
Anti-3-Methylcrotonyl-Coa Carboxylase 1 antibody
Anti-3-Methylcrotonyl-Coa Carboxylase Biotin-Containing Subunit antibody
Anti-3-Methylcrotonyl-Coa -Carbon Dioxide Ligase Subunit Alpha antibody
Anti-MCCC1 antibody
Anti-MCCA antibody

Information sourced from Uniprot.org