Host: | Rabbit |
Applications: | WB/IHC-P/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:1000-1:5000IHC-P:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | MCCC1 |
Gene ID: | 56922 |
Uniprot ID: | MCCA_HUMAN |
Immunogen Region: | 640-725 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 640-725 of human MCCC1 (NP_064551.3). |
Immunogen Sequence: | VSSQETQGGPLAPMTGTIEK VFVKAGDKVKAGDSLMVMIA MKMEHTIKSPKDGTVKKVFY REGAQANRHTPLVEFEEEES DKRESE |
Post Translational Modifications | Acetylated. |
Function | Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism. |
Protein Name | Methylcrotonoyl-Coa Carboxylase Subunit Alpha - MitochondrialMccase Subunit Alpha3-Methylcrotonyl-Coa Carboxylase 13-Methylcrotonyl-Coa Carboxylase Biotin-Containing Subunit3-Methylcrotonyl-Coa -Carbon Dioxide Ligase Subunit Alpha |
Database Links | Reactome: R-HSA-196780Reactome: R-HSA-3371599Reactome: R-HSA-70895 |
Cellular Localisation | Mitochondrion Matrix |
Alternative Antibody Names | Anti-Methylcrotonoyl-Coa Carboxylase Subunit Alpha - Mitochondrial antibodyAnti-Mccase Subunit Alpha antibodyAnti-3-Methylcrotonyl-Coa Carboxylase 1 antibodyAnti-3-Methylcrotonyl-Coa Carboxylase Biotin-Containing Subunit antibodyAnti-3-Methylcrotonyl-Coa -Carbon Dioxide Ligase Subunit Alpha antibodyAnti-MCCC1 antibodyAnti-MCCA antibody |
Information sourced from Uniprot.org