| Host: | Rabbit |
| Applications: | WB/IHC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (620-670 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MCCC1 |
| Gene ID: | 56922 |
| Uniprot ID: | MCCA_HUMAN |
| Immunogen Region: | 620-670 aa |
| Specificity: | This antibody detects endogenous levels of MCCA at Human/Mouse/Rat |
| Immunogen: | Synthesized peptide derived from the human MCCA at the amino acid range 620-670 |
| Function | Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism. |
| Protein Name | Methylcrotonoyl-Coa Carboxylase Subunit Alpha - MitochondrialMccase Subunit Alpha3-Methylcrotonyl-Coa Carboxylase 13-Methylcrotonyl-Coa Carboxylase Biotin-Containing Subunit3-Methylcrotonyl-Coa -Carbon Dioxide Ligase Subunit Alpha |
| Database Links | Reactome: R-HSA-196780Reactome: R-HSA-3371599Reactome: R-HSA-70895 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Methylcrotonoyl-Coa Carboxylase Subunit Alpha - Mitochondrial antibodyAnti-Mccase Subunit Alpha antibodyAnti-3-Methylcrotonyl-Coa Carboxylase 1 antibodyAnti-3-Methylcrotonyl-Coa Carboxylase Biotin-Containing Subunit antibodyAnti-3-Methylcrotonyl-Coa -Carbon Dioxide Ligase Subunit Alpha antibodyAnti-MCCC1 antibodyAnti-MCCA antibody |
Information sourced from Uniprot.org