Host: |
Rabbit |
Applications: |
WB/IHC |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (620-670 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000IHC-P 1:50-300 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
MCCC1 |
Gene ID: |
56922 |
Uniprot ID: |
MCCA_HUMAN |
Immunogen Region: |
620-670 aa |
Specificity: |
This antibody detects endogenous levels of MCCA at Human/Mouse/Rat |
Immunogen: |
Synthesized peptide derived from the human MCCA at the amino acid range 620-670 |
Function | Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism. |
Protein Name | Methylcrotonoyl-Coa Carboxylase Subunit Alpha - MitochondrialMccase Subunit Alpha3-Methylcrotonyl-Coa Carboxylase 13-Methylcrotonyl-Coa Carboxylase Biotin-Containing Subunit3-Methylcrotonyl-Coa -Carbon Dioxide Ligase Subunit Alpha |
Database Links | Reactome: R-HSA-196780Reactome: R-HSA-3371599Reactome: R-HSA-70895 |
Cellular Localisation | Mitochondrion Matrix |
Alternative Antibody Names | Anti-Methylcrotonoyl-Coa Carboxylase Subunit Alpha - Mitochondrial antibodyAnti-Mccase Subunit Alpha antibodyAnti-3-Methylcrotonyl-Coa Carboxylase 1 antibodyAnti-3-Methylcrotonyl-Coa Carboxylase Biotin-Containing Subunit antibodyAnti-3-Methylcrotonyl-Coa -Carbon Dioxide Ligase Subunit Alpha antibodyAnti-MCCC1 antibodyAnti-MCCA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance