Anti-MC5R antibody (1-100) [S5744RM] (STJ11105744)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Melanocortin Receptor 5 (1-100) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S5744RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MC5R |
| Gene ID | 4161 |
| Uniprot ID | MC5R_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MNSSFHLHFLDLNLNATEGN LSGPNVKNKSSPCEDMGIAV EVFLTLGVISLLENILVIGA IVKNKNLHSPMYFFVCSLAV ADMLVSMSSAWETITIYLLN |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MC5 Receptor (P33032). |
Additional Info
| Tissue Specificity | Expressed in the brain but not in the melanoma cells. |
| Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins. |
| Protein Name | Melanocortin Receptor 5Mc5-RMc-2 |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418555Reactome: R-HSA-9856649 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Melanocortin Receptor 5 antibodyAnti-Mc5-R antibodyAnti-Mc-2 antibodyAnti-MC5R antibody |
Information sourced from Uniprot.org