• Western blot analysis of extracts of various cell lines, using (STJ11105744) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s.

Anti-MC5R antibody (1-100) [S5744RM] (STJ11105744)

SKU:
STJ11105744

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Melanocortin Receptor 5 (1-100) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S5744RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:100-1:500
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MC5R
Gene ID: 4161
Uniprot ID: MC5R_HUMAN
Immunogen Region: 1-100
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MC5 Receptor (P33032).
Immunogen Sequence: MNSSFHLHFLDLNLNATEGN LSGPNVKNKSSPCEDMGIAV EVFLTLGVISLLENILVIGA IVKNKNLHSPMYFFVCSLAV ADMLVSMSSAWETITIYLLN
Tissue Specificity Expressed in the brain but not in the melanoma cells.
Function Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.
Protein Name Melanocortin Receptor 5
Mc5-R
Mc-2
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-418555
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Melanocortin Receptor 5 antibody
Anti-Mc5-R antibody
Anti-Mc-2 antibody
Anti-MC5R antibody

Information sourced from Uniprot.org

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