| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MC3R |
| Gene ID: | 4159 |
| Uniprot ID: | MC3R_HUMAN |
| Immunogen Region: | 1-100 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MC3R (P41968). |
| Immunogen Sequence: | MNASCCLPSVQPTLPNGSEH LQAPFFSNQSSSAFCEQVFI KPEVFLSLGIVSLLENILVI LAVVRNGNLHSPMYFFLCSL AVADMLVSVSNALETIMIAI |
| Tissue Specificity | Brain, placental, and gut tissues. |
| Function | Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain. |
| Protein Name | Melanocortin Receptor 3 Mc3-R |
| Database Links | Reactome: R-HSA-375276 Reactome: R-HSA-418555 Reactome: R-HSA-9856649 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Melanocortin Receptor 3 antibody Anti-Mc3-R antibody Anti-MC3R antibody |
Information sourced from Uniprot.org