| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-MC2R/ACTHR (N-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 40kDa band observed in Human Skin lysates (calculated MW of 33.9kDa according to NP_000520.1). The observed molecular weight corresponds to earlier findings in literature with d |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | MC2R |
| Gene ID: | 4158 |
| Uniprot ID: | ACTHR_HUMAN |
| Immunogen Region: | N-Term |
| Accession Number: | NP_000520.1 |
| Immunogen Sequence: | ENINNTARNNSDC |
| Function | Receptor for corticotropin (ACTH). This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase (cAMP). |
| Protein Name | Adrenocorticotropic Hormone ReceptorActh ReceptorActh-RAdrenocorticotropin ReceptorMelanocortin Receptor 2Mc2-R |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418555Reactome: R-HSA-5579031 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Adrenocorticotropic Hormone Receptor antibodyAnti-Acth Receptor antibodyAnti-Acth-R antibodyAnti-Adrenocorticotropin Receptor antibodyAnti-Melanocortin Receptor 2 antibodyAnti-Mc2-R antibodyAnti-MC2R antibodyAnti-ACTHR antibody |
Information sourced from Uniprot.org