| Short Description : | Mouse monoclonal anti-Mannose-Binding Protein C (Ala18-Asp244) for use in WB, IHC and ELISA in Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/ELISA |
| Host: | Mouse |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
| Clonality : | Monoclonal |
| Clone ID : | 2H3 |
| Isotype: | IgG2b |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | Protein G purified from mice ascities |
| Formulation: | 0.01M PBS |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Gene Symbol: | Mbl2 |
| Gene ID: | 17195 |
| Uniprot ID: | MBL2_MOUSE |
| Immunogen: | Mammalian cells-derived recombinant Mouse MBL2/MBP-C (Ala18-Asp244) |
| Immunogen Region: | Ala18-Asp244 |
| Function | Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. |
| Protein Name | Mannose-Binding Protein CMbp-CMannan-Binding ProteinRa-Reactive Factor P28a SubunitRarf/P28a |
| Database Links | Reactome: R-MMU-166662Reactome: -MMU-166663 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Mannose-Binding Protein C antibodyAnti-Mbp-C antibodyAnti-Mannan-Binding Protein antibodyAnti-Ra-Reactive Factor P28a Subunit antibodyAnti-Rarf/P28a antibodyAnti-Mbl2 antibody |
Information sourced from Uniprot.org