| Host: | Mouse |
| Applications: | WB/IHC/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
| Short Description : | Mouse monoclonal antibody anti-Mannose-Binding Protein C (Ala18-Asp244) is suitable for use in Western Blot, Immunohistochemistry and ELISA research applications. |
| Clonality : | Monoclonal |
| Clone ID : | 2H3 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2b |
| Formulation: | 0.01M PBS |
| Purification: | Protein G purified from mice ascites |
| Concentration: | 1 mg/mL |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
| Gene Symbol: | Mbl2 |
| Gene ID: | 17195 |
| Uniprot ID: | MBL2_MOUSE |
| Immunogen Region: | Ala18-Asp244 |
| Immunogen: | Mammalian cells-derived recombinant Mouse MBL2/MBP-C (Ala18-Asp244) |
| Function | Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. |
| Protein Name | Mannose-Binding Protein CMbp-CMannan-Binding ProteinRa-Reactive Factor P28a SubunitRarf/P28a |
| Database Links | Reactome: R-MMU-166662Reactome: -MMU-166663 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Mannose-Binding Protein C antibodyAnti-Mbp-C antibodyAnti-Mannan-Binding Protein antibodyAnti-Ra-Reactive Factor P28a Subunit antibodyAnti-Rarf/P28a antibodyAnti-Mbl2 antibody |
Information sourced from Uniprot.org
