![Anti-Mast cell tryptase antibody [SM4997] (STJA0004997)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/180060/403333/STJA0004997_1__84501.1738950400.png?c=1 "Anti-Mast cell tryptase antibody [SM4997] (STJA0004997)")
![Anti-Mast cell tryptase antibody [SM4997] (STJA0004997)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/180060/403334/STJA0004997_2__82464.1738950400.png?c=1 "Anti-Mast cell tryptase antibody [SM4997] (STJA0004997)")
![Anti-Mast cell tryptase antibody [SM4997] (STJA0004997)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/180060/403333/STJA0004997_1__84501.1738950400.png?c=1 "Anti-Mast cell tryptase antibody [SM4997] (STJA0004997)")
| Host: | Mouse |
| Applications: | IHC/IF |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Mast cell tryptase is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
| Clonality : | Monoclonal |
| Clone ID : | SM4997 |
| Conjugation: | Unconjugated |
| Formulation: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: | IHC/IF (H) 1:200-1:500 |
| Storage Instruction: | Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
| Gene Symbol: | TPSAB1 |
| Gene ID: | 7177 |
| Uniprot ID: | TRYB1_HUMAN |
| Immunogen: | Synthesized peptide derived from human Mast cell tryptaseT |
| Function | Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates. |
| Protein Name | Tryptase Alpha/Beta-1Tryptase-1Tryptase ITryptase Alpha-1 |
| Database Links | Reactome: R-HSA-1592389 |
| Cellular Localisation | SecretedReleased From The Secretory Granules Upon Mast Cell Activation |
| Alternative Antibody Names | Anti-Tryptase Alpha/Beta-1 antibodyAnti-Tryptase-1 antibodyAnti-Tryptase I antibodyAnti-Tryptase Alpha-1 antibodyAnti-TPSAB1 antibodyAnti-TPS1 antibodyAnti-TPS2 antibodyAnti-TPSB1 antibody |
Information sourced from Uniprot.org