| Host: | Mouse | 
| Applications: | IHC/IF | 
| Reactivity: | Human | 
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. | 
| Short Description : | Mouse monoclonal antibody anti-Mast cell tryptase is suitable for use in Immunohistochemistry and Immunofluorescence research applications. | 
| Clonality : | Monoclonal | 
| Clone ID : | SM4997 | 
| Conjugation: | Unconjugated | 
| Formulation: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. | 
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. | 
| Dilution Range: | IHC/IF (H) 1:200-1:500 | 
| Storage Instruction: | Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. | 
| Gene Symbol: | TPSAB1 | 
| Gene ID: | 7177 | 
| Uniprot ID: | TRYB1_HUMAN | 
| Immunogen: | Synthesized peptide derived from human Mast cell tryptaseT | 
| Function | Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates. | 
| Protein Name | Tryptase Alpha/Beta-1Tryptase-1Tryptase ITryptase Alpha-1 | 
| Database Links | Reactome: R-HSA-1592389 | 
| Cellular Localisation | SecretedReleased From The Secretory Granules Upon Mast Cell Activation | 
| Alternative Antibody Names | Anti-Tryptase Alpha/Beta-1 antibodyAnti-Tryptase-1 antibodyAnti-Tryptase I antibodyAnti-Tryptase Alpha-1 antibodyAnti-TPSAB1 antibodyAnti-TPS1 antibodyAnti-TPS2 antibodyAnti-TPSB1 antibody | 
Information sourced from Uniprot.org
 
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