| Short Description : | Rabbit monoclonal anti-Mast Cell Chymase for use in WB and IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | R02-7D8 |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | Affinity Chromatography |
| Dilution Range: | WB 1:500-1:1000IHC 1:50-1:100 |
| Formulation: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | CMA1 |
| Gene ID: | 1215 |
| Uniprot ID: | CMA1_HUMAN |
| Immunogen: | A synthesized peptide derived from human Mast Cell Chymase |
| Tissue Specificity | Mast cells in lung, heart, skin and placenta. Expressed in both normal skin and in urticaria pigmentosa lesions. |
| Function | Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. |
| Protein Name | ChymaseAlpha-ChymaseMast Cell Protease I |
| Database Links | Reactome: R-HSA-1433557Reactome: R-HSA-1592389Reactome: R-HSA-2022377 |
| Cellular Localisation | SecretedCytoplasmic GranuleMast Cell Granules |
| Alternative Antibody Names | Anti-Chymase antibodyAnti-Alpha-Chymase antibodyAnti-Mast Cell Protease I antibodyAnti-CMA1 antibodyAnti-CYH antibodyAnti-CYM antibody |
Information sourced from Uniprot.org
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