| Post Translational Modifications | Autoubiquitinated leading to degradation (short half-life). |
| Function | Mitochondrial E3 ubiquitin-protein ligase that plays a crucial role in the control of mitochondrial morphology by acting as a positive regulator of mitochondrial fission. May play a role in the prevention of cell senescence acting as a regulator of mitochondrial quality control. Promotes ubiquitination of FIS1, DNM1L and MFN1. |
| Protein Name | E3 Ubiquitin-Protein Ligase Marchf5Membrane-Associated Ring Finger Protein 5Membrane-Associated Ring-Ch Protein VMarch-VMitochondrial Ubiquitin LigaseMitolRing Finger Protein 153Ring-Type E3 Ubiquitin Transferase Marchf5 |
| Cellular Localisation | Mitochondrion Outer MembraneMulti-Pass Membrane ProteinEndoplasmic Reticulum MembraneAuthors Show That The Protein Can Be Detected In Endoplasmic ReticulumAuthors Show Its Presence Only In Mitochondria |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Marchf5 antibodyAnti-Membrane-Associated Ring Finger Protein 5 antibodyAnti-Membrane-Associated Ring-Ch Protein V antibodyAnti-March-V antibodyAnti-Mitochondrial Ubiquitin Ligase antibodyAnti-Mitol antibodyAnti-Ring Finger Protein 153 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Marchf5 antibodyAnti-MARCHF5 antibodyAnti-MARCH5 antibodyAnti-RNF153 antibody |
Information sourced from Uniprot.org
