| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-E3 ubiquitin-protein ligase MARCHF4 (301-350 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MARCHF4 |
| Gene ID: | 57574 |
| Uniprot ID: | MARH4_HUMAN |
| Immunogen Region: | 301-350 aa |
| Specificity: | MARCH4 Polyclonal Antibody detects endogenous levels of 40606 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human MARCH4 at the amino acid range 301-350 |
| Function | E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. |
| Protein Name | E3 Ubiquitin-Protein Ligase Marchf4Membrane-Associated Ring Finger Protein 4Membrane-Associated Ring-Ch Protein IvMarch-IvRing Finger Protein 174Ring-Type E3 Ubiquitin Transferase Marchf4 |
| Cellular Localisation | Golgi Apparatus MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Marchf4 antibodyAnti-Membrane-Associated Ring Finger Protein 4 antibodyAnti-Membrane-Associated Ring-Ch Protein Iv antibodyAnti-March-Iv antibodyAnti-Ring Finger Protein 174 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Marchf4 antibodyAnti-MARCHF4 antibodyAnti-KIAA1399 antibodyAnti-MARCH4 antibodyAnti-RNF174 antibody |
Information sourced from Uniprot.org